Ashlyn Bassiri, Ph.D.

Pharmacovigilance Lead, Hematology/Liver Programs, Spark Therapeutics

Ashlyn Bassiri


Ashlyn Bassiri grew up in Ohio as the daughter of a paramedic. “I really developed a love of potentially being a doctor,” she says. “That’s exactly what I envisioned doing with my career.”

As fate would have it, Bassiri became involved with research at an immunology lab in college. Today, she’s the pharmacovigilance lead in the hematology/liver programs at Philadelphia’s Spark Therapeutics. “I’ve had the opportunity to use my immunology experience from the beginning, from doing very basic science and identification of new targets, to actually getting immunology medicine into the clinic,” says Bassiri, who now lives in Radnor.

Bassiri’s research focuses on helping those who suffer from forms of hemophilia. “They have a gene defect where one of the proteins that helps blood clot is either nonfunctional or almost nonfunctional, so patients have to take a replacement clotting factor,” she says. “We’re trying to deliver a copy of the gene—not replace it. This makes an additional clotting factor—and if they have none, some clotting factor—to improve their quality of life.”

Part of Bassiri’s research involves patient reactions to specific medicines in clinical trials. And though she doesn’t interact with patients, it does harken back to her early love of medicine. “When you hear about how patients are doing on the medicine you’re trying to develop, it’s a huge confidence booster and a huge driver to keep moving forward,” she says.

Edit ModuleShow Tags

Agathe Boidin

CEO and Director of U.S. Operations, Orchestra

Ashlyn Bassiri, Ph.D.

Pharmacovigilance Lead, Hematology/Liver Programs, Spark Therapeutics

Betty Lou Bettner, Ph.D., LPC

Author and Psychologist

Bindu Kolli Jayne

Title IX Coordinator, Swarthmore College

Eileen McDonnell

CEO and Chairman of the Board, Penn Mutual

Erin Entrada Kelly

Author and Adjunct Professor, Rosemont College

Jennifer Opdahl

Owner and Designer, PowerBeads by Jen

Jess Edelstein and Sarah Ribner

Cofounders, PiperWai

Kathy Romano

On-Air Personality, WMMR’s "Preston & Steve Show," BEN FM’s "Her Story"

Kelly Green

Executive Director, Help Hope Live

Laura Kelly

Owner/Founder, The Handwork Studio

Lauren McComas

President and Artistic Director, SALT Performing Arts

Libby Landry

Hospital Director, VRC Specialty Hospital

Lori Pastore

Owner, AME Salon and Spa

Maurine McGeehan

Executive Director, Lower Merion Conservancy

Rev. Chimère Holmes

Licensed Psychotherapist, Thomas Jefferson University

Rowena Castillo Lesher

Program Director, Horizons

Ryan Hammond

Executive Director, Eagles Autism Challenge

Stephanie Cohen

Vice President and CFO, Operation Warm